Identify two reasons why Maria will have tissue ischemia. How might this lead to hypoxia?

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Identify two reasons why Maria will have tissue ischemia. How might this lead to hypoxia?

In your discussion, be sure to integrate your knowledge of advanced pathophysiology across the lifespan with the clinical implications for the advanced practice nurse Case Study Assignment Requirements: * Make sure all of the topics in the case study have been addressed. * Cite at least three references in your case study paper; this may include peer-reviewed journal articles, textbooks, or evidence-based practice websites to support the content. * All reference sources must be within 5 years. * Do not use sources such as Wikipedia or UpToDate as a reference. * Assignments must have at least four full pages of analytic content, double-spaced (the cover and reference pages do not count in the page count, but must be included with the assignment), and follow APA 7th edition format. Assignment: Six Case Studies to Choose From (Taken from Units 1 & 2 Readings) Case Study 1: Cellular Adaptation, Injury, and Death Maria is a sedentary, 68-year-old woman who is overweight. She complains that her hands and feet are always cold, and she tires quickly when cleaning the house. At her most recent visit to her doctor, her blood pressure was 184/98 mm Hg. She has edema around her ankles and legs, and her physician is concerned about an echocardiogram that indicates Maria has an enlarged heart. 1. Identify two reasons why Maria will have tissue ischemia. How might this lead to hypoxia? 2. What are the two early and reversible changes that occur to tissue cells when they are hypoxic? 3. What specific type of cellular adaptation has taken place in Maria’s enlarged heart? What made you come to this conclusion? Before finalizing your work, it is important to: * Review Case Study Assignment Requirements (described above) and the Case Study Assignment Grading Rubric (under the Course Resources), to ensure you have completed all required elements of the assignment. * Make sure to review your chosen case study carefully to make sure you have effectively answered all questions asked. * Utilize spelling and grammar checks to minimize errors. * Follow the conventions of Standard English (correct grammar, punctuation, etc.). * Make sure your assignment is original, insightful, and utilizes your logic and critical thinking skills; that your assignment is well-organized, with superior content, style, and mechanics. ***Utilize APA 7th edition format.**** * Be diligent about APA formatting including paraphrasing and direct quotations, utilizing appropriate in-text citations, and referencing your sources. ****A Turnit in a score of less than 20% is needed****